In this paradigm-changing study, researchers found that short fragments of circular DNA that encode cancer genes are far more common in cancer cells than previously believed. They showed that ...

Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself DURHAM, N.C. -- Like its viral cousins, a somewhat parasitic DNA sequence called a ...

But work in the past 10 years suggests those DNA tidbits, which are circular, aren’t just some cellular debris. Cancer cells use the circles to rapidly grab or shed genes linked to tumor growth ...

They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression ...

can transform into cancer cells." "We were also able to show that certain types of circular DNA may accelerate neuroblastoma growth," explains Dr. Koche. "Testing for their presence may therefore ...

elegans, as well as in three human cell types. What Is Circular DNA? The DNA molecules that make up the genes and chromosomes in our cells are rope-like strands, free at both ends and shaped like ...

They hijack a little-known piece of the cell's DNA repair function to close ... The retrovirus HIV, which causes AIDS, is also known to form circular DNA. "I think these elements are the source ...

can transform into cancer cells." "We were also able to show that certain types of circular DNA may accelerate neuroblastoma growth," explains Dr. Koche and adds: "Testing for their presence may ...

If you ask a biologist if humans have circular DNA, they are likely to say 'no.' That is because eukaryotic cell nuclei have linear chromosomes, while prokaryotes have circular nucleoids and plasmids.

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes ...