These findings could help guide the design of tailor-made chromosomes not just for yeast, but for plants and animals too-where it is even more essential to preserve genetic balance. Ultimately ...

They also found that after the extra chromosome was removed, genes tied to nervous system development were more active and ...

Japanese researchers have successfully eliminated the extra chromosome responsible for Down syndrome using CRISPR gene ...

“Essentially, we did a complete overhaul of the old approach to HAC [human artificial chromosome] design and delivery,” study author Dr. Ben Black said in a press release. “The work is likely to ...

Machine learning-aided scoring of synthesis difficulties for designer chromosomes. Science China Press. Journal Science China Life Sciences Funder National Natural Science Foundation of China ...

Finally, we can design experiments to test the impact and function of these previously unexplored parts of the Y chromosome,” Miga said. It’s been shown that people with Y chromosomes can lose some or ...

The Y chromosome can disappear over time in human males, which may introduce a number of health problems. While the exact trigger for such degeneration is unknown, environmental factors can play a ...

Trisomy 2 is a chromosomal abnormality, where human cells are found to contain an extra copy of chromosome 2. This is a rare but recurrent finding in myelodysplastic syndrome, a form of cancer ...

The Y chromosome has seen significant changes over the course of human evolution. "In comparison to the X, the Y is tiny. There are only 45 genes on the Y chromosome, ...

Machine learning-aided scoring of synthesis difficulties for designer chromosomes. Science China Press. Journal Science China Life Sciences DOI 10.1007/s11427-023-2306-x ...