The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

An international team of researchers co-led by Job Dekker, PhD, at UMass Chan Medical School, have identified rules that tell cells how to fold DNA into the tightly packed, iconic X-shaped chromosomes ...

While this internal rivalry is usually hard to see, it becomes clearer when it involves genes on the X and Y chromosomes, which determine the sex of mammals. A hidden battle between X and Y ...

This competition, or arms race, is typically hard to observe–except when the genes in question live on the X and Y chromosomes, which determine the sex of offspring in mammals. In mice ...