Chiral drug-like building blocks by nickel-catalyzed enantioselective olefin cross-coupling. Oct 28, 2022. New method uses enantioselective nickel catalysis to synthesize multifunctional chiral ...

Abstract: Drug recommendation as an auxiliary medical tool has garnered significant attention from researchers in recent years, primarily due to its potential in identifying effective combination ...

Their creation, dubbed the “chiral vortex,” is an entirely new structure of light that acts like a molecular detective, capable of distinguishing between nearly identical chemical twins. At the heart ...

More information: Vojtěch Dočekal et al, Organocatalytic desymmetrization provides access to planar chiral [2.2]paracyclophanes, Nature Communications (2024).DOI: 10.1038/s41467-024-47407-0 ...

Every year, Clarivate curates a list of drugs with the potential of becoming breakthrough and blockbuster medicines in the coming year. This year, 13 molecules made it to the 2024 Drugs to Watch list, ...

Overall, the development of chiral antitubercular drugs represents an important area of research for the treatment of TB. These drugs have the potential to overcome drug resistance and offer more ...

List and MacMillan developed a different method — asymmetric organocatalysis — to obtain enantiopure chiral compounds. 1,2 Asymmetric organocatalysis uses small organic catalysts ...

In chiral drug synthesis that uses bioorthogonal chemistry within complex biological milieu, asymmetric transfer hydrogenation (ATH), which utilizes safe hydrogen donors instead of high pressure H ...