drug Resist Updat：联合使用ALK抑制剂和SRC抑制剂有望延缓肺癌细胞产生抗药性. 对细胞蛋白质组的仔细研究表明，SRC抑制剂和ALK抑制剂的联合使用可以 ...

The chiral-switch concept. Chiral switches are chiral drugs that have already been CLAIMED, approved and marketed as racemates or as mixtures of diastereomers, but have since been redeveloped as ...

Scientists eliminate drug side effects by manipulating molecular chirality Date: May 19, 2020 Source: Hong Kong Baptist University Summary: Scientists have developed a novel technique that can ...

New synthesis strategy for chiral drugs: Versatile chiral chemical species from aldehydes. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2019 / 01 / 190109102435.htm.

Since many drugs exhibit chirality-dependent effectiveness, our new method should facilitate synthesis and development of pharmaceuticals and their precursors. Advanced Search Home ...

List and MacMillan developed a different method — asymmetric organocatalysis — to obtain enantiopure chiral compounds. 1,2 Asymmetric organocatalysis uses small organic catalysts ...

From 2001 to 2011, the US Food and Drug Administration approved 9 single-enantiomer drugs with racemic precursors. None showed pre-approval evidence of improved efficacy over the racemic precursor.

As chemists have learned through tragedies like the birth defects caused when the chiral drug thalidomide racemized in pregnant women, losing control over a molecule’s configuration can be fatal.

Overall, the development of chiral antitubercular drugs represents an important area of research for the treatment of TB. These drugs have the potential to overcome drug resistance and offer more ...

Sidebar: New Ways To Separate Enantiomers Photo: Malboro Photo SUCCESS IN SEPARATION: Sepracor researchers found that the S-enantiomer of Prozac worked well in preventing migraine, says Dean Handley.

Chiral Drugs - Opportunities for Indian Pharmaceutical Industry Dr M D Nair Tuesday, September 4, 2001, 08:00 Hrs [IST] While discussing the Indian Pharmaceutical Industry and its compulsions to grow ...