This approach involves modifying existing polymer chains by introducing new chemical groups after their ... phosphonate ester groups exhibit fire resistance and temperature responsiveness, even ...

Therefore, IN has become an important target for antiviral drug discovery. However, mutants have emerged, such as E92Q/N155H and G140S/Q148H, which confer resistance to raltegravir (RAL), the first IN ...

† Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States ‡ Department of Structural Biology, School of ...