Hinchcliffe and colleagues took the acentrosomal cells produced by microsurgery 5 and monitored them after mitosis (or failure in cytokinesis); most seemed to arrest in G1 phase and did not ...

leading to cell cycle arrest in the G1 phase. Further investigation into the role of CDK4/CDK6 in ESCC was conducted through CRISPR-mediated gene knockout experiments. The depletion of CDK4/CDK6 ...

PHEC-66's impact extends to the modulation of cell cycle progression, particularly evident in the sub G1 and sub G1/G1 phases ...

Maintaining treatment with CDK4/6 inhibitors significantly suppresses the growth of breast cancer cells, even after drug resistance has developed, according to new research.