Abstract: This study presents a fully automated membrane segmentation technique for immunohistochemical tissue images with membrane staining, which is a critical task in computerized ...

Scientists use electric fields to detect aging 'zombie' cells without dyes or labels, offering a breakthrough for ...

In clinical settings, biopsies are routinely used to determine cancer type and grade based on tumor cell morphology, as determined via histochemical or immunohistochemical staining. Unfortunately, in ...

Background: The clinical benefit of T-DXd in advanced breast cancer with hormone receptor-positive (HR+), HER2-IHC 0 with membrane staining (MS+) tumors in the DESTINY-Breast06 trial has drawn ...

Bacteria can precisely adjust their membrane lipid compositions to control the biophysical properties of their membranes, which allows them to thrive in various physical environments. Here ...

How one of the oldest components of the human immune system can trigger a mysterious and little-understood syndrome.

Biofouling on silicone implants causes serious complications such as fibrotic encapsulation, bacterial infection, and implant failure. Here we report the development of antifouling, antibacterial ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

For cell membrane staining, hMMES1 cells were labeled with PKH 26 (red fluorescent, MCE). PKH 26 was dissolved in DMSO to obtain 1 mM stock solution of PKH 26. The stock solution was diluted with PBS ...

To stain for pZap70 and pPLCγ1, cells were blocked for 1 h with 5% BSA in PBS and then either stained with rabbit anti-pPLCγ1 (Cell Signaling, #2821, 1/100) ... Epitope distance to the target cell ...

You don’t have to be a numismatist to enjoy looking at coins under a microscope. An enthusiast will be able to find pockets of lead, patterns of lustre and flaws from heating, cooling and striking ...