Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane ...

Researchers have confirmed that mammalian BK ion channels regulate themselves using a “ball-and-chain” mechanism. A recent ...

FAs are important in cellular processes such as membrane structure, energy storage, and signaling. However, challenges remain ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden 's lab at the McGovern Institute for Brain Research are ...

The study presents a useful computational analysis of how the ratio between excitatory and inhibitory neural numbers affects coding capacity. The authors show that increasing the proportion of ...

This important study characterizes and validates a new activity marker - fast labelling of engram neurons (FLEN) - which is transiently active and driven by cFos, allowing the monitoring of intrinsic ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings ...

More information: Zhao Yang et al, Identification, structure, and agonist design of an androgen membrane receptor, Cell (2025). DOI: 10.1016/j.cell.2025.01.006 Journal information: Cell ...