The cost of a lifetime of care for a severe spinal cord injury can be as high as $5 million. About Lineage Cell Therapeutics, Inc. Lineage Cell Therapeutics is a clinical-stage biotechnology company ...

BACKGROUND: Neonatal hypoxic-ischemic (HI) brain injury is one of the leading causes of long-term neurological morbidity in newborns. Current treatment options for HI brain injury are limited, but ...

In this study, we used hypoxia/reoxygenation (H/R) H9c2 rat cardiomyocyte model to simulate the clinical MIRI and explore the protective effects of borneol on H/R induced cardiomyocyte injury and its ...

If you have hypoxic or anoxic brain injury, it could put you in a coma. When that happens, it looks like you’re asleep and you won’t respond if you’re called or stimulated in some way.

In summary, levels of hypoxia encountered by inflammatory cells in pathophysiological situations increase neutrophil degranulation, deploying harmful proteins and proteases to the extracellular milieu ...

Hypoxia refers to tissues or cells having too little oxygen to function correctly. ... Hypoxia most commonly results from lung conditions but may stem from a heart or liver condition or an injury.

3.3. Small extracellular vesicles derived from hypoxic cultured UC-MSCs rescued neuronal cell injury and maintained cell viability. We used irradiated (10 Gy) SCs to construct a cell injury model and ...

Comprehensive single-cell transcriptomic analysis revealed that in the animals treated with the advanced reperfusion technology, genes encoding proteins involved in oxidative injury, stress ...

Figure 4.MicroRNA (miR)-210 overexpression alleviated the injury induced by hypoxia in PC-12 cells. (A–D) Overexpression of miR-210 increased cell viability, cell migration, cell invasion, and ...

Objective—We explored the role of endoplasmic reticulum (ER)–mitochondria Ca2+ cross talk involving voltage-dependent anion channel-1 (VDAC1)/glucose-regulated protein 75/inositol 1,4,5-trisphosphate ...