The targeting vector was linearized by SfiI digestion (New England Biolabs), precipitated by phenol/chloroform and electroporated into PRX-B6N C57BL/6N embryonic stem (ES) cells. Screening for ...

Glioblastoma (GBM) is the most aggressive and lethal form of brain cancer, with a median survival of only 15 months despite ...

β2-Integrin Adhesion Regulates Dendritic Cell Epigenetic and Transcriptional Landscapes to Restrict Dendritic Cell Maturation and Tumor Rejection. Cancer Immunology Research , 2021; DOI: 10.1158 ...

Dendritic cells are divided into Type 1 (DC1) and Type 2 (DC2) dendritic cells. Each type fulfills different functions: DC1 provide an immune response to bacteria and viruses, DC2 protect against ...

As part of the immune system, dendritic cells are essential for fighting body cells that have degenerated or are infected with a virus. They trigger an immune response by presenting protein ...

As part of the innate immune system, dendritic cells are in the body's first line of defense against infections. They detect pathogens and coordinate the immune response. An international team led ...

There is an elevated amounts of iron in persister cancer cells. In these cells, iron is taken up preferentially by CD44-mediated endocytosis, where iron binds to hyaluronic acid and this glycan ...