However, most solid tumors, such as triple negative breast cancer (TNBC), do not have identifiable surface markers to distinguish themselves from normal cells, thus it is challenging to selectively ...

Dubodencel, also known as DOC1021, is a first-in-class, double-loaded autologous dendritic cell therapy that uniquely combines tumor lysate and amplified tumor-derived mRNA. The immunotherapy is made ...

A paradigm shift in the way we treat spinal injuries is now in sight, with the world's first regenerative cell therapy being granted approval for a registrational Phase I clinical trial.

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of HNSCC, but many patients still exhibit poor responses due to insufficient T cell infiltration and impaired dendritic cell (DC) ...

State Key Laboratory of Radiation Medicine and Protection, The Fourth Affiliated Hospital of Soochow University, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative ...

T regulatory cells, dendritic cells, macrophages, natural killer cells and neutrophils which are being developed as alternative immune cell therapies. NExT makes gene delivery quicker and less ...

Federally funded Johns Hopkins team finds the virus ‘reprograms’ neutrophils to impair production of immune cells critical for fighting COVID New study in @ScienceTM (bit.ly/3YUnScG) by ...

Figure 2: T cell stimulatory capacity and morphology of CD40L-matured PDCs. Figure 3: Viability of DC subsets after stimulation with influenza and intracellular MxA expression. Figure 4 ...

In biology classes from high school through university, I learned that mitochondria are little objects that reside within each cell and serve as “powerhouses,” combining oxygen and food to ...