Discover how bitter taste receptors in the intestines affect aging. A new study identifies specific receptors linked to metabolic changes, inflammation, and lipid metabolism. Learn how these ...

At the core of timing-dependent plasticity is the N-methyl-D-aspartate (NMDA) receptor, one of the three classes of neurotransmitter receptors located on the postsynaptic side of excitatory ...

Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered ...

Get Instant Summarized Text (Gist) A novel GPS NMR method enabled precise tracking of motions within the β 1-adrenergic GPCR, revealing that the receptor exists in a dynamic equilibrium among ...

In a surprising discovery, scientists have found that the heart possesses 'sweet taste' receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can ...

Summary: New research has revealed the diverse assembly and regulation of Type-A GABA receptors (GABAARs), which are crucial for balancing brain activity.Using cryogenic electron microscopy, ...

To assess how well our pipeline reflects previously documented inhibitory receptors, we confirmed that all the 52 proteins known for their ITIM-mediated immune inhibitory effects, such as PD-1 or ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain ...

GPCRs (G protein-coupled receptors), also known as 7 transmembrane domain receptors, are the largest receptor family in the human genome, with ≈800 members. GPCRs regulate nearly every aspect of human ...

Nuclear receptors are receptors that bind to a ligand that has crossed the cell membrane, after which the ligand-bound receptor binds to DNA to regulate gene expression. These receptors are key ...

The receptors are part of your body’s endogenous opioid system, which deals with pain, reward, and addiction. They’re present on nerve cells, mainly in your central nervous system (CNS) and gut.