G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

"Delta receptors are located throughout the body on pathways and neurons that transmit pain signals to the brain," said Jay McLaughlin, Ph.D., a professor of pharmacodynamics in the UF College of ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

1Children’s Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas. 10Howard Hughes Medical Institute, UT Southwestern Medical Center, ...

Officers found the knife in the driver’s side door and confiscated green, leafy cathinone, commonly known as “khat,” from the defendant, the complaint alleges. The stimulant, which typically ...

Amar H. Mehsin allegedly had a drug called Khat, which contains the stimulant cathinone. Mehsin was charged with criminal possession of a weapon. He was released under the supervision of probation ...

This manuscript presents important findings on a bacterial effector involved in plant symbiotic signaling. The effector proteolytically targets a key receptor while its activity is counteracted by ...

This manuscript describes important findings on a rhizobial effector, its cleavage, and legume receptors involved in symbiosis. The evidence supporting the main claims is solid, though some ...

The complement system plays crucial roles in innate immunity and inflammatory responses. The anaphylatoxin C3a mediates pro-inflammatory and chemotactic functions through the G protein-coupled ...