The fraction of sp3-hybridized carbons (Fsp3) and the fraction of stereogenic carbons (FCstereo) are two widely employed scores of molecular complexity with strong links to biologically relevant ...

Large-scale nanoarrays of single biomolecules enable high-throughput assays while unmasking the underlying heterogeneity within ensemble populations. Until recently, creating such grids which combine ...

EU report warns of surging synthetic drug threats in Ireland, with potent opioids, cathinones and edibles endangering public health ...

Cathinone is the psychoactive ingredient in khat, a plant chewed for its stimulating effects. Seven new cathinone derivatives were identified in Europe in 2024. In 2023, authorities dismantled 53 ...

Resistin-like molecule β (RELMβ) belongs to the RELM protein family, which also includes RELMα, RELMγ, and resistin. RELMβ is produced predominantly by colon goblet cells ( 7 ), is induced by the ...

CLERMONT-FERRAND, France—Michelin will invest over $60 million to construct an initial industrial demonstration unit for a bio-sourced, non-toxic molecule, known as a "sleeping giant." 5-HMF, also ...

Company enters option agreement with JiKang Therapeutics to in-license novel APJ agonist antibody New composition of matter IP filed for chemically distinct, orally active, and highly potent small ...

Blocking the molecule protected lab mice from mental decline, the researchers say. An important player in the brain’s immune system, STING also may be a key contributor to Parkinson’s disease, ...

The immune molecule STING has been identified as a key driver of brain inflammation, amyloid plaque, and tau tangle formation in Alzheimer's disease. Blocking STING in mice reduced neuronal damage ...