资讯

Although rapid progress is being made in many areas of molecular cardiology, issues pertaining to the origins of heart-forming cells, the mechanisms responsible for cardiogenic induction, and the ...
Developed in collaboration with REPROCELL, CELLvo ™ Atrial Cardiomyocyte delivers non-genetically modified human heart cells that are chamber specific and derived from iPS (stem) cells SAN ANTONIO, ...
and no factor identified to promote mammalian cardiomyocyte proliferation has been translated into medical practice. Therefore, finding a novel factor will be vital. Here, we established a live cell ...
We would like to draw your attention to changes in our revision policy that we have made ... and that more rigorous data is needed to show in situ endothelial cell expression of cardiomyocyte genes ...
Here, we use a combination of bulk RNASeq, single-cell RNASeq datasets, in situ mRNA hybridization, and most importantly ATAC-Seq of FACS-isolated nuclei, to show that cardiac ECs actively express ...
The adult mammalian heart has limited regenerative capacity, mostly attributable to postnatal cardiomyocyte cell cycle arrest. In the last 2 decades, numerous studies have explored cardiomyocyte cell ...
Figure 1. The main cardiac cell types and their interactions with endothelial cells and cardiomyocytes. Selected known paracrine factors mediating endothelial cell—cardiomyocyte cross-talk ...
The peripheral blood of the WT parabiont was collected from the retro-orbital sinus and the red blood cells were lysed by ACK lysing buffer (Lonza). Cardiomyocyte-depleted cardiac small cells were ...
Direct reprogramming of human cardiac fibroblasts (HCFs) into cardiomyocytes may hold great potential for this purpose. We reported previously that induced cardiomyocyte-like cells (iCMs) can be ...
Using genetic fate mapping to mark resident myocytes in combination with long‐term BrdU pulsing, we investigated the origins of postnatal cardiomyogenesis in the normal, infarcted and cell‐treated ...