With these preliminary findings that it is in principle possible to control dedifferentiation and thus the division of cardiac muscle cells, the scientists investigated whether repair processes could ...

We therefore hoped to trigger changes in gene activities by reprogramming energy metabolism to turn cell division ability back on in cardiac muscle cells." In further studies, the scientists were able ...

Since mammals cannot regenerate cardiac muscle cells on their own, heart transplants are currently the only clinically viable option for patients suffering (or likely to suffer) heart failure.

Heart attacks cause both long- and short-term problems. In the short-term, the death of cardiac muscle cells can cause a critical drop in the heart's ability to function. Over the long haul ...

Scientists have for the first time succeeded in generating beating cardiac muscle cells from special stem cells. They may provide a new approach for the treatment of heart attacks. Myocardial ...

This model system, due to its multicellularity ... "We differentiate induced pluripotent stem cells into cardiac muscle cells, fibroblasts and endothelial cells. Then we mix them with mesenchymal ...

Grafts of human cardiac muscle cells, grown from embryonic stem cells ... of arrhythmias (irregular heart rhythms) in a guinea pig model of myocardial infarction (commonly known as a heart ...

and is a cardiac muscle grown in a laboratory from cardiac cells derived from induced pluripotent stem cells embedded in a collagen hydrogel. The simulation of this treatment in monkeys was the ...