Endothelial cells (ECs) are a highly specialized cell type with marked diversity between different organs or vascular beds. Cardiac ECs are an important player in cardiac physiology and ...

Autoimmunity is increasingly recognized as a key contributing factor in heart muscle diseases. The functional features of cardiac autoimmunity in humans remain ... will abrogate myocardial ...

A study led by a physician-scientist at the University of Arizona College of Medicine–Tucson's Sarver Heart Center identified ...

Abstract: The 3D segmentation of the left ventricle (LV) in cardiac MRI is a challenging problem, due to the presence of other anatomical structures and artifacts (outliers) around the LV. In this ...

Here, we have generated a three-dimensional human engineered cardiac tissue, termed biowire, from human embryonic stem cell-derived CMs to investigate the effects of chronic (7 day) treatment with ...

University of Savoy Mont Blanc, CNRS, Grenoble INP (Institute of Engineering and Management University Grenoble Alpes), LEPMI, Université Grenoble-Alpes, 38000 Grenoble, France ...

Researchers at UCL and the Francis Crick Institute have, for the first time, identified the origin of cardiac cells using 3D images of a heart forming in real-time, inside a living mouse embryo.

Axon guidance cues direct nerves in the heart during development, disease and regeneration. These cues determine cardiac innervation patterning by regulating the balance between chemo-attraction and ...

Circadian disruption, occurring in shift work, sleep deprivation, or dementia, increases the risk of sarcopenia, the age-related loss of muscle mass and strength. The cell-intrinsic and extrinsic ...

This model system, due to its multicellularity ... "We differentiate induced pluripotent stem cells into cardiac muscle cells, fibroblasts and endothelial cells. Then we mix them with mesenchymal ...