This model system, due to its multicellularity ... "We differentiate induced pluripotent stem cells into cardiac muscle cells, fibroblasts and endothelial cells. Then we mix them with mesenchymal ...

ESC-CM engraftment did not correlate with functional improvements in a rodent model where cells are transplanted 1 month after myocardial infarction. ESC-CM transplantation was safe as no tumors or ...

Vascular smooth muscle cells (VSMCs), in response to a myriad of injurious stimuli ... Importantly, Suv39h1 deletion significantly ameliorated neointima formation in mice in both the carotid artery ...

Tevard Biosciences, Inc., a privately held biotechnology company pioneering tRNA-based therapies to cure a broad range of genetic diseases, presented preclinical data demonstrating the potential of ...

Gum disease bacteria can reach the heart, causing damage that raises AFib risk. Good oral hygiene may help protect heart ...

Researchers at UCL and the Francis Crick Institute have, for the first time, identified the origin of cardiac cells using 3D ...

Here, we have generated a three-dimensional human engineered cardiac tissue, termed biowire, from human embryonic stem cell-derived CMs to investigate the effects of chronic (7 day) treatment with ...

Researchers have discovered how cholesterol can disrupt the internal functioning of the heart by accumulating in the ...

A study led by a physician-scientist at the University of Arizona College of Medicine–Tucson's Sarver Heart Center identified ...

An international team of researchers has uncovered a groundbreaking discovery in the fight against heart disease. They found ...