The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.

To further investigate their involvement in cardiac and skeletal muscle function, future work should involve more in ... mutations in LINC complex–associated proteins impact human cardiomyocyte ...

The heart is composed of multiple cell types ... Does the agent prevent cardiac dilation, improve intrinsic muscle function, reduce fibrosis and improve cardiac vascular supply/demand balance?

U.S. FDA successfully completed Pre-License Inspection; Company expects facility will meet all requirements to support licensure Advisory Committee meeting scheduled for July 30, 2025 Mid-cycle ...

Cardiac muscle cells have an intrinsic ability to sense and respond to mechanical load through a process known as mechanotransduction. In the heart, this process involves the conversion of mechanical ...

Werdan, U., Herpich, C., Norman, K., Chadt, A., Al-Hasani, H., Völler, H., Salzwedel, A., Vogel, H.: Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing ...