Goldstein has reviewed the results of four double-blind comparative trials in which 368 patients were treated with quinapril and 338 with comparative therapies (i.e. captopril, enalapril or placebo).

After a single-blind run-in period, we assigned patients, in a double-blind fashion, to one of three groups: 2336 patients were assigned to receive enalapril at a dose of 5 or 10 mg twice daily ...

In patients treated with enalapril and aspirin, the relative risk of death at the end of the study was 1.23 (95% confidence interval [CI], 0.99-1.53) compared with 0.86 (95% CI, 0.63-1.16) for ...

Compared with users of enalapril, users of perindopril switched less often, while users of captopril switched significantly more often. Most ACE inhibitor switchers started using an ARB (75.0%).

However, use of enalapril or captopril was associated with higher mortality compared with ramipril: adjusted hazard ratios (and 95% CIs) were 1.10 (1.04–1.16) for enalapril and 1.13 (1.01–1.26) for ...

These medicines include benazepril, captopril, enalapril, lisinopril and ramipril. Angioedema is a potentially deadly reaction that can occur at any time (even after months or years of safe use).