Alcohol-linked cancer deaths have doubled in the U.S. in the past 30 years. Alcohol associated cancer deaths have doubled in the United States over the past three decades, disproportionately ...

Steep cuts to federal medical research grants this year have now disrupted millions in awards once backed by former President Joe Biden's "Cancer Moonshot" initiative, after the Trump ...

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Abstract: In this paper, we focus on mechanical characterization of human umbilical vein endothelial cell (HUVEC) and mesenchymal stem cell (MSC) co-cultured spheroids. HUVEC/MSC co-cultured spheroid ...

Abstract: The cancer cell spheroids, as one of the mostly utilized 3D in vitro model in laboratory, can provide a highly predictive value for the pre-clinical drug research of anticancer therapies.

This article reports the results of pulsed ultrasound enhanced penetration of nanosized fluorescent particles into MCF-7 breast cancer spheroids (300−350 μm diameter) as a function of particle size ...

They found that cancer cells within the droplets aggregated to form tumor spheroids with hypoxic cores and exhibited proliferation markers typical of in vivo tumors. The tumor spheroids also ...

Until recently, conventional methods used to create such tumor spheroids were time-consuming, produced inconsistent results and involved high setup costs. By vibrating a suspension of cancer cells ...

To include endothelial cells (EC), a previous study has combined human umbilical vein EC (HUVEC) with lung fibroblasts and different pancreatic cancer cell lines to form 3D PDAC spheroids. The ...

Organoids are constructed from gastric cancer patients with four molecular subtypes according to TCGA. Organoids were dissociated into a single cell to make a co-culture spheroid with HUVEC cells.