Understanding The Migration Of Cancer Cells Date: June 24, 2008 Source: Goethe University Frankfurt Summary: Lamellipodia and filopodia are dynamic surface extensions of the cell which play a ...

Disrupting the SETD2-HTT-HIP1R association inhibited actin methylation, caused defects in actin dynamics and impaired cell migration, an important function of cancer cells. Related Stories ...

Lamellipodia and filopodia are dynamic surface extensions of the cell which play a pivotal role in cell migration, invasion and wound healing. Biochemists from Frankfurt University have succeeded ...

Using EMT cancer cells to drive epithelial cancer cell migration and guide tumor spheroid disaggregation Jun 15, 2022 Cancer cells behave like Goldilocks: Resolving the mystery of cancer cell steering ...

The work is published in Nature, in the paper, “Extracellular fluid viscosity enhances cell migration and cancer dissemination. “This is really the first time that the viscosity of the ...

A dendritic meshwork of short and highly branched actin filaments might constitute their main structural component. ... Understanding the migration of cancer cells (2008, ...

Physicists model cell migration to learn how cancer cells navigate tissue. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2023 / 01 / 230111150818.htm ...

image: Super-resolution microscopy image of a cell. With fluorescent markers the prometastatic factor ANGPTL4 is labelled in magenta, the molecule FMNL2 in green, and the actin cell skeleton in white.

Counterintuitively, cells move faster in thicker fluids. New research on breast cancer cells explains why, and reveals the role that fluid viscosity plays in metastasis.

More information: Holly Merta et al, Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration, Cell Reports (2025). DOI: 10.1016/j.celrep ...