Cells have a calcium signalling toolkit with many components that can be mixed and matched to create a wide range of spatial and temporal signals. This versatility is exploited to control ...

Several Ca 2+-dependent pathways are described that modulate gene expression by signal transduction to transcriptional regulators. In cardiomyocytes, well-characterized signaling patterns in this ...

This observation therefore provides a simple mechanism by which the structural dynamics of CaMKII establishes the link between calcium signaling and the morphological plasticity of dendritic spines.

Although several MCUC components have been identified, the molecular basis of mitochondrial calcium signaling networks and their remodeling upon changes in uniporter activity have not been assessed.

1 Department of Biochemistry, Microbiology and Bio-informatics, Faculty of Science and Engineering; Neuroscience Axis, CHU de Québec Research Center (CHUL), Laval University, Québec, QC, Canada 2 ...