资讯

Neuronal calcium sensor-1 (NCS-1) regulates various neuronal functions. Although it is expressed in the heart, very little is known about its cardiac functions.
The plasma membrane calcium pumps (PMCAs ... PMCA4 in cardiac fibroblasts has revealed a paracrine pathway that governs cardiomyocyte hypertrophy, offering insight into potential anti-hypertrophic ...
Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) adversely modulates myocyte calcium ... pathways. Here, we focus on new developments with small-molecule inhibitors of cardiac hypertrophy ...
The cellular targets for myostatin and activin A in muscle and the role of satellite cells in mediating muscle hypertrophy induced by inhibition of this signaling pathway have not been fully ...
Although there is broad, though not universal, agreement that aberrations in calcium handling are responsible for triggering pathological cardiac growth, the mechanisms that enable cardiac ...
Signaling by adrenergic agonists stimulates cardiac performance. Binding of catecholamines to seven-transmembrane-spanning receptors, which couple through G-proteins to adenylate cyclase, results ...