Calcium benefits the body by supporting bone health and possibly reducing the risk of colon cancer. Calcium may also help improve blood pressure and boost better weight control. Adequate calcium is ...

Here, we show that pharmacologic activation of the ISR kinases HRI or GCN2 promotes adaptive mitochondrial elongation and prevents mitochondrial fragmentation induced by the calcium ionophore ...

A zero calcium score with high cholesterol may mean a person is at a lower risk of coronary heart disease. It means imaging does not show a buildup of calcified plaque in the heart’s blood vessels.

Intracellular kinases play a ubiquitous role in signaling pathways within cells. Receptor tyrosine kinases function at the beginning of a number of signal transduction cascades, whereas ...

Ionophores have been used for many years in the beef and poultry industries for improved feed efficiency and control of coccidiosis. Generally, ionophores are considered safe and effective in the ...

Introduction: Bryostatin-1, a potent agonist of the protein kinase C, has been studied for HIV and cancer therapies. In HIV research, it has shown anti-HIV effects during acute infection and ...

Dinitrophenol uncouples oxidative phosphorylation within the respiratory chain by acting as a proton ionophore. The leak it creates in the inner mitochondrial ... Additionally, ATP depletion leads to ...

This manuscript describes valuable findings on the expression pattern of orexin receptors in the midbrain and how manipulating this system influences several behaviors, such as context-induced ...