Some medications and supplements can make your birth control less effective at preventing pregnancy. These include some ...

In a nutshell Cinnamaldehyde in cinnamon supplements can potentially interact with medications by affecting drug-processing ...

The simplified requirements for Camzyos are expected to ease prior contraindications, thereby simplifying treatment and ...

FDA approves Camzyos label update easing echo monitoring and lifting drug interaction limits, supported by 3.5 years of safety data and real-world use ...

SaveHealth assesses the relative benefits of Zoloft vs. Lexapro, comparing their usage, effectiveness, tolerability, ...

Princeton: Bristol Myers Squibb has announced that the U.S. Food and Drug Administration (FDA) has updated the U.S.

Bristol Myers Squibb today announced that the U.S. Food and Drug Administration (FDA) has updated the U.S. Prescribing Information for CAMZYOS® (mavacamten, 2.5 mg, 5 mg, 10 mg, 15 mg capsules), ...

Scientists explored selectively blocking the CYP3A4 protein responsible for breaking down large swaths of approved drugs, providing a way to improve drug efficacy.

Bristol Myers Squibb today announced the Phase 3 ODYSSEY-HCM trial evaluating Camzyos (mavacamten) for the treatment of adult patients with symptomatic New York Heart Association (NYHA) class II-III ...

Concomitant use of CAMZYOS with certain cytochrome P450 inhibitors or discontinuation ... CAMZYOS is primarily metabolized by CYP2C19 and CYP3A4 enzymes. Concomitant use of CAMZYOS and drugs ...

One of the optimized inhibitors, SCM-08, exhibited a 46-fold difference in CYP3A4 inhibition versus CYP3A5 and avoids other CYP proteins involved in off-target binding of existing CYP inhibitors.