The drug is cleared by cytochrome P450 (CYP)3A4 metabolism ... Blood levels of eplerenone are increased by inhibitors of CYP3A4, such as ketoconazole and saquinavir. About 50% is bound by plasma ...

is a substrate of cytochrome P450 (CYP)2C8, CYP2C9, and CYP3A4, and to a minor extent, CYP2C19 and CYP2J2. ETR has the potential for drug-drug interaction (DDI) with CYP2C8, CYP2C9, and CYP3A4 when ...

For example, Ubrelvy can interact with certain drugs called strong CYP3A4 inhibitors, such as clarithromycin. Ubrelvy is taken by adults to treat certain kinds of migraine episodes. An interaction ...

Call for immediate medical help if you have any of the following symptoms. Taking Vicodin or Percocet at the same time as any cytochrome P450 3A4 inhibitors (drugs that block the activity of the ...

[35] Clinically, one of the most important drug interactions induced by omeprazole is a 25 ± 50% reduction in clearance of diazepam owing to competitive inhibition of CYP2C19. This effect is not ...

2021). Pirtobrutinib is a CYP3A4 substrate, so it is recommended to avoid strong CYP3A4 inhibitors and inducers during pirtobrutinib therapy whenever possible (Pharmacist’s Application to Practice, ...

HMG-CoA reductase inhibitors, better known as statins ... by the same liver enzyme, cytochrome P450 3A4 (CYP3A4). If you take both vitamin D and a statin, they will compete for the enzyme.

Medically reviewed by Mary Choy, PharmD Klonopin (clonazepam) is a medication in the benzodiazepine (BZD) family that's ...

Calcium-rich foods like milk, cheese, and yogurt can bind to certain antibiotics, such as tetracycline and ciprofloxacin, ...