For patients receiving moderate CYP3A inhibitors, the dose of venetoclax was reduced by 50%. Cytoreduction with hydroxyurea was permitted to decrease the white blood cell count to less than 10 × 10 10 ...

Brings A, Lehmann ML, Foerster KI, Burhenne J, Weiss J, Haefeli WE, Czock D. Perpetrator effects of ciclosporin (P-glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the ...