DDIs are an important cause of adverse drug reactions and exact a large toll on the health care system. DDI for warfarin mainly involve moderate to strong inhibitors/inducers of cytochrome P450 (CYP) ...

New data from Phase 2 SPARTAN Study show antifibrotic and anti-inflammatory action of FILSPARI and its impact on B cell and complement pathways in IgAN Travere Therapeutics, Inc., (Nasdaq: TVTX) today ...

The clinical response (efficacy and toxicity) of lupus nephritis patients receiving cyclophosphamide varied. 1 Cyclophosphamide is a pro-drug metabolized by hydroxylation via the CYP2C19 and CYP2B6 ...

The Seventh People’s Hospital of Wenzhou, Wenzhou, Zhejiang 325018, PR China Institute of Molecular Toxicology and Pharmacology, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, ...

But CYP2B6*6 is vital in determining Artemisinin pharmacokinetics hence treatment outcome. Interindividual variability may mediate variable responses to artemisinin therapy among malaria patients.

However, little is known about the frequency of alleles CYP2B6, CYP2C8, and CYP2D6 in an Amazonian population, especially with vivax malaria. Therefore, this study aimed to determine the frequency of ...

Consider discontinuation if there is ocular pain and another cause cannot be determined. Effect of CYP1A2 and CYP2B6 inducers Co-administration with strong CYP1A2 inducers or CYP2B6 inducers will ...

The active form of clopidogrel is via 2 step oxidative process mediated by hepatic CYP450 enzymes. CYP2B6 encoded by CYP2B6 gene is important in both the oxidative steps. CYP2B6 polymorphisms may ...

21 scientific presentations, including 7 late breakers, showcase the breadth of UCB's portfolio, reinforcing commitment to improving the lives of ...