The clinical response (efficacy and toxicity) of lupus nephritis patients receiving cyclophosphamide varied. 1 Cyclophosphamide is a pro-drug metabolized by hydroxylation via the CYP2C19 and CYP2B6 ...

Bpgbio Inc. has synthesized bifunctional compounds comprising an E2 ubiquitin ligase binding ligand covalently linked to an estrogen receptor α (ER-α; ESR1) targeting moiety through a linker acting as ...

Introduction: Coral restoration efforts increasingly focus on enhancing larval settlement and post-settlement survival. However, the species-specific efficacy of different settlement inducers remains ...

Treeline Biosciences Inc. has divulged proteolysis targeting chimeras (PROTACs) comprising cereblon (CRBN) ligands coupled to a Bcl-2-like protein 1 (Bcl-xl; Bcl-X; BCL2L1) targeting moiety via a ...

Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida 33136, United States Peggy and Harold Katz Family Drug ...

Travere Therapeutics today announced that the Company will present three abstracts at the upcoming International Podocyte Conference.

SAN DIEGO, June 03, 2025--(BUSINESS WIRE)--Travere Therapeutics, Inc., (Nasdaq: TVTX) today announced that the Company will present seven abstracts at the upcoming European Renal Association (ERA ...

Department of Drug and Health Sciences, University of Catania, 95125 Catania, Italy Department of Drug and Health Sciences, University of Catania, 95125 Catania, Italy CERNUT - Research Centre on ...

SAN DIEGO--(BUSINESS WIRE)--$TVTX--Travere Therapeutics, Inc., (Nasdaq: TVTX) today announced that the Company will present seven abstracts at the upcoming European ...

New data from Phase 2 SPARTAN Study show antifibrotic and anti-inflammatory action of FILSPARI and its impact on B cell and complement pathways in IgAN Travere Therapeutics, Inc., (Nasdaq: TVTX) today ...