Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor ...

Humanized mouse models dominate the market type segment, expected to maintain the fastest growth through 2030 due to their utility in drug discovery ...

One ingredient that you’ll see on many cans is taurine. Taurine is an amino acid often added to energy drinks for its ...

A study of human tumor cells implanted in mice from the MacPherson Lab at Fred Hutch describes a new way to screen for the ...

CRISPR-Cas9 enzymes can be used to edit genes ... The researchers conducted proof-of-concept experiments in human cells and a mouse model of retinitis pigmentosa, finding that the bespoke enzymes ...

A big breakthrough is being hailed in the world of gene editing, with the first custom-designed treatment using CRISPR ...

It takes about two months to generate a gene-targeted founder mouse with CRISPR technology. Typically, the positive founders are transferred to the investigator. CRISPR reagents are injected into ...

Researchers from Tel Aviv University utilized CRISPR to cut a single gene from cancer cells of head and neck tumors—and successfully eliminated 50% of the tumors in model animals. This study was ...

CRISPR-Cas9 enzymes can be used to edit genes ... The researchers conducted proof-of-concept experiments in human cells and a mouse model of retinitis pigmentosa, finding that the bespoke enzymes ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Acuitas’ LNP enabled delivery of three doses of a personalized CRISPR therapy with ... the development of more predictive mouse and nonhuman primate (NHP) models to assess factors related ...