CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

The study generated approximately 1,300 CRISPR lines to influence tomato traits, including flavor, nutrient uptake, and pathogen response.

More information: Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6 mediated gene editing in hematopoietic stem cells, Cell Reports Medicine (2025). DOI: 10.1016 ...

Conservationists and some community members fear that altering mosquito populations could destabilise ecosystems or pose ...

Apart from ethical considerations, more importantly, ecological & evolutionary role of the species has to be considered when discussing a tool that could wipe out an entire species.

A guide RNA (orange) shepherds the base editor to the typo. The base editor is a version of a DNA-cutting enzyme called CRISPR/Cas9 that has been altered so that it nicks one of two DNA strands at ...

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GEN ranks not only the top 10 publicly traded developed of editing-based therapies, but the top five privately held companies ...

“How awesome is it that we’re at this point?” said Nessan Bermingham, who co-founded and led Intellia, one of the first CRISPR companies, until 2017.