Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 genome engineering has revolutionised biomedical science and we are standing on the cusp of medical transformation. The ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

The promising field of genomics has undergone rapid evolution over the past decade. Genomics includes the study of a complete set of genes, their work process and way of interacting with each other ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

In a major leap forward, researchers at the University of Geneva have discovered two proteins—MLF2 and RBM15—that play a key ...

得益于最近的研究，Braun及其团队识别出两种调节染色质重塑的蛋白——MLF2和RBM15。“这是首次发现，”日内瓦大学医学院遗传医学与发育系博士生、论文第一作者Hanna Schwämmle表示。“我们的发现表明，这两种调节因子可能成为与染色质重塑紊乱相关的疾病的潜在治疗靶点——并且可能提供比当前治疗方案更安全的治疗方法。” ...

Scientists have identified two proteins involved in regulating chromatin remodelling which could be promising therapeutic ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

SLC35B1 transports ATP into the ER, and its structure offers potential for targeted therapies in diseases linked to ER stress. A team of scientists has solved a long-standing question in cell biology ...