近日，北京大学化学与分子工程学院本科校友、美国威斯康星麦迪逊大学博士毕业生、目前正在斯坦福大学从事博士后研究的朱彦宇和所在团队研发出一种高时空分辨率的活细胞 DNA 成像技术 Oligo-LiveFISH。该技术基于 sgRNA ...

CRISPR-Cas13 vs CRISPR/Cas9: What is the difference? Although both are CRISPR-Cas systems, Cas9 and Cas13 are actually quite different in terms of how they work. This is because CRISPR-Cas9 uses a ...

Scientists from Zhejiang University have developed a novel delivery vehicle for CRISPR-Cas9 that is more effective than lipid nanoparticles (LNPs) in treating lung cancer. Rapid liquid nitrogen ...

Exosomes show potential to treat myriad conditions, including cancer and inflammation, but experts are divided on whether the therapies are ready for the limelight. Imagine a future where, instead of ...

CRISPR/Cas9-based therapeutics require a safe and effective delivery system to more directly and specifically target cancer cells present in the colon. This review will present pertinent evidence for ...

Researchers are working to reveal potential threats to the efficacy of CRISPR/Cas9 gene editing, even when it appears to be working as planned. A Rice University lab is leading the effort to ...

We also compare the advantages of various nano-delivery systems and their applications to deliver CRISPR/Cas9 for disease treatment. Nano-delivery systems can be modified to fulfill the tasks of ...

Understanding the mechanisms of development and disease often requires the ability to remove gene function from specific tissues. The CRISPR/Cas9 system can mutate any gene by Cas9-mediated DNA ...

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in ...

When CRISPR/Cas9 came online in 2012, it offered scientists a tool to do exactly this – cut genes. The Cas9 enzyme searches through DNA, using a "guide RNA" to look for a specific sequence, and makes ...