To define the molecular basis for rituximab resistance we developed several RRCL and demonstrated changes in CD20 expression/structure and membrane reorganization following rituximab therapy.

“To decode the molecular interplay of endogenous CD20 on B cells with therapeutic mAbs, three-dimensional (3D) volumetric super-resolution fluorescence imaging methods are needed that provide a ...

The CD20 protein presents a unique arrangement, featuring four membrane-spanning domains. Notably, both the amino and carboxy termini of the protein are positioned within the cytoplasm. An intriguing ...