Please use one of the following formats to cite this article in your essay, paper or report: APA. ACROBiosystems. (2025, January 24). Antibody drug development: Targeting CD20 and CD3.

Impaired Ca++ mobilization in rituximab-resistant cells (RRCL) is associated with changes in the structure of CD20 antigen, down-regulation of Bax/Bak pro-apoptotic proteins and up-regulation of the ...

Tedder, TF, Streuli, M, Schlossman, SF, Saito, H. Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes. Proc Natl Acad Sci U S A 1988;85:208-212.

Structure of CD20The CD20 protein presents a unique arrangement, featuring four membrane-spanning domains. Notably, both the amino and carboxy termini of the protein are positioned within the ...

“To decode the molecular interplay of endogenous CD20 on B cells with therapeutic mAbs, three-dimensional (3D) volumetric super-resolution fluorescence imaging methods are needed that provide a ...

Antibodies directed against the protein CD20, which is expressed by immune cells known as B cells, are used to treat B cell non-Hodgkin lymphoma and rheumatoid arthritis. Despite this, the ...

BAT4306F is an ADCC-enhanced CD20 monoclonal antibody that has demonstrated enhanced potency in preclinical studies with potential to be a “best-in-class” therapeutic. “Initiating our Phase ...