在呼吸道抵御流感病毒、新冠病毒等病原体侵袭的免疫前线，驻留记忆T细胞（Tissue-resident memory T cells, ...

Objective Chronic hepatitis B virus (HBV) infection is characterised by HBV-specific CD8+ T cell dysfunction that has been linked to Tcell exhaustion, a distinct differentiation programme associated ...

In response to infections, naive CD8 T cells give rise to effector and memory T cells. However, eliciting long-lived memory CD8 T cells remains a challenge for many infections. DNA demethylation of ...

This valuable manuscript provides an interesting account documenting the role of resident CD56(br) NK cells in driving interaction with dendritic cells that attract CD8+ T cells to the pancreas cancer ...

Comprehensive transcriptomic, epigenomic, and flow cytometric profiles of primary CD8+ T cell subsets implicate T cell exhaustion in pathophysiology. We show that T cells in ME cases are ...

A variant form of LGL leukemia involves a specific T cell called CD8+. CD8+ T cells are T cells that carry the co-receptor CD8. A co-receptor is a surface protein that makes antigen receptors more ...

This important study extends our understanding of how regulatory T cells can modulate the function of effector CD8 T cells. The evidence supporting the claims of the authors is solid and direct test ...

Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction ...

(Figure 6). We can conclude that T-cell-related immune pathways are significantly enriched in CCL5/CCR5-related genes. According to different surface markers, T cells can be divided into CD4+ and CD8+ ...

Heart-tropic chemokines expressed by Temra CD8 + cells such as CCL5 may become important therapeutic targets in the prevention and treatment of ICI myocarditis and other types of pathological cardiac ...

1 Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands 2 Center for Translational Immunology, University Medical Center Utrecht ...