Abstract: A swarm intelligence technique called the bees algorithm is formulated to build synthetic networks of the budding yeast cell-cycle. The resulting networks contain the original fixed points ...

Ubiquitylation-dependent CMG helicase disassembly is the final step during DNA replication in eukaryotes. This study identifies a second pathway for replisome disassembly in budding yeast cells, which ...

C. albicans can grow in a variety of morphological forms, ranging from budding yeast to pseudohyphae and hyphae, where the latter is a more pathogenic form. Different signaling pathways and ...

Given the importance of this issue, all the steps that lead to cell separation are finely regulated. The budding yeast Saccharomyces cerevisiae is a unicellular eukaryotic organism that divides ...

Abstract: Symptoms of fungal diseases can be similar to those of COVID-19, and lab tests are necessary to determine the precise infections a person is suffering from. Candida albicans (C. albicans) is ...

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This finding identifies novel signaling modality in yeast for the control of TORC1 function. TORC1 is regulated by a sophisticated signaling network that, in humans, includes two well-defined channels ...

Budding yeast, Saccharomyces cerevisiae (S. cerevisiae), benefiting from its fast proliferation, short lifespan, easy maintenance, and fully-sequenced genome, has been extensively used as a model ...

But how does this switching ability occur? “When we got rid of the Sir2 gene, we saw less of the true hyphae form,” says Zhao, first author and a PhD candidate in biological sciences, College of Arts ...

albicans' transition from ovoid yeast to thread-like hypha. C. albicans cells that were missing the Sir2 gene were less likely to form true hyphae in lab experiments than cells of the same species ...

This is interesting, she says, because both the "tiny round yeast form" and the "elongated hyphae form" are "essential to infection," helping C. albicans invade different niches of the human body.