To realize an efficient hybridization of oligonucleotides, a DNA self-assembled monolayer (SAM) composed of branched probe DNA containing single- and double-stranded portions was prepared on a gold ...

Hepatitis B virus (HBV) infection remains a major global health concern, necessitating the development of sensitive and reliable diagnostic methods. In this study, we propose a novel approach to ...

Genomic and epigenomic patterns within DNA molecules are pivotal for a broad spectrum of in-vitro diagnostic applications, including companion diagnostics (Fridlyand et al, 2013; Van Neste et al, 2011 ...

Currently, several technologies have been developed for HCV RNA detection, such as branch DNA assay, real-time quantitative polymerase chain reaction coupled with reverse transcription (RT-qPCR), ...

EpiCypher, a leader in epigenomic technologies, has introduced two innovative DNA methylation sequencing assays - CUTANA® meCUT&RUN and Multiomic CUT&RUN - that offer scalable, high-resolution ...

The discovery that FANCM’s domains physically interact suggested they might functionally cooperate in migrating these branched DNA structures. To test this, we developed a novel real-time assay using ...

As ESR1 mutations are often subclonal, highly sensitive blood-based circulating tumour (ct)DNA assays are preferred. 40 Testing for PI3K/AKT/PTEN pathway alterations is also essential after ...

Assessing a tumor-agnostic circulating tumor DNA assay for uveal melanoma surveillance and metastatic disease monitoring. Emily Gordon, Diana McDonnell, Shaheer Khan, Brian P. Marr Journal of Clinical ...

Tissue-free circulating tumor DNA assay and patient outcome in a phase III trial of FOLFOX-based adjuvant chemotherapy (Alliance N0147). Diana I. Segovia, Aaron Hardin, Thereasa A. Rich, Steven R.

The Ho was highest in the Tongjiang goat at 0.2931, whereas the Chengdu grey goat had the lowest Ho at 0.2507. The He of six goat populations was remarkably similar (Supplementary Table S5).Conversely ...