Biliverdin reductase catalyses the last step in haem degradation and produces the major lipophilic antioxidant bilirubin via reduction of biliverdin, using NAD(P)H as a cofactor. Despite the ...

In cases of a condition called jaundice, a compound called bilirubin turns a person's skin and eyes yellow. It's usually a ...

Biliverdin reductase A (BLVRA), an enzyme that converts biliverdin to bilirubin, has recently emerged as a key regulator of the cellular redox cycle. However, the role of BLVRA in the aging ...

Scientists say they have new experimental evidence of a novel role for bilirubin, a natural yellow pigment found in the body, ...

A research team has investigated biliverdin reductase, the enzyme producing bilirubin -- a substance linked with jaundice -- from biliverdin (BV). Two BV molecules were found at the enzyme ...

New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.

They determined that just like biliverdin, the biliverdin nanoparticles had strong absorbance at wavelengths of 365 nm and 680 nm, with fluorescence and photoacoustic imaging contrast at these ...

Biliverdin, a byproduct of hemoglobin breakdown, sometimes stains the fur of puppies in the womb, giving them a temporary green tint. Though biliverdin primarily affects fur color in these rare ...

Led by M.D./Ph.D. candidate David Baraño, the research team demonstrated that, without biliverdin reductase, human cancer cells and brain cells from rats experienced much more damage and cell ...

Biliverdin is further reduced to bilirubin by the enzyme biliverdin reductase. Carbon monoxide can activate guanylyl cyclase (GC) and lead to the formation of cyclic guanosine monophosphate (cGMP).

Led by M.D./Ph.D. candidate David Baraño, the research team demonstrated that, without biliverdin reductase, human cancer cells and brain cells from rats experienced much more damage and cell ...

Neuroscientist Solomon Snyder and colleagues at Johns Hopkins Medical School in Baltimore discovered why the body makes bilirubin at all, when its immediate precursor, biliverdin, is easily excreted: ...