V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Akademik Kukhar St, Kyiv 02094, Ukraine ...

School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China ...

An alternative to Paxlovid, the only antiviral pills approved by the US Food and Drug Administration to treat COVID-19, is on ...

BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today reported financial results for the ...

The agreement is firmly geared towards the back end with an upfront fee of $30 million that gives Roche’s Genentech unit a buy-in to Bicycle’s bicyclic peptide drug discovery platform across a ...

1-Indanone (> 99%), methylmagnesium bromide solution (3.0 M in diethyl ether), acyl donors vinyl acetate, isopropenyl acetate, ethyl acetate, ethyl trifluoroacetate and vinyl butyrate, and immobilized ...

Bicycle Therapeutics has developed a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle) product platform, and will gain funding for phase 1 and phase 1b clinical trial ...

Chengdu Tetrahedral Drug Research Co. Ltd. has synthesized bicyclic derivatives acting as β-lactamase (bacterial) inhibitors reported to be useful for the treatment of bacterial infection.

Merck KGaA has patented substituted bicyclic transcriptional coactivator YAP1/transcriptional enhancer factor (TEAD) and/or TAZ/TED interaction inhibitors reported to be useful for the treatment of ...

At present, the treatment of NPP is still dominated by drug use. The first-line drugs for the treatment of NPP include gabapentin (gabapentin and pregabalin), bicyclic antidepressants (TCAS) and ...