更棘手的是，RA滑膜组织中纤维母细胞样滑膜细胞(FLSs)的恶性增殖与自噬(Autophagy)-凋亡(Apoptosis)平衡紊乱密切相关——这种失衡被证实与高迁移率族蛋白1(HMGB1)过表达及Beclin 1-Bcl-2复合体结合减少直接相关，但具体调控机制尚未阐明。 针对这一科学难题，西安交通 ...

Autophagy is a self-preservation mechanism in which your body removes damaged or dysfunctional parts of cells in order to regenerate newer, healthier cells. “Auto” means self and “phagy ...

Investopedia / Nez Riaz The tier 1 capital ratio is a measure of a bank's financial strength, calculated as the ratio of a bank’s core tier 1 capital to its total risk-weighted assets.

该综述聚焦自噬（Autophagy）与癌症干细胞（CSCs ... 自噬的双重作用使得治疗策略需根据肿瘤类型和微环境进行精准调控。生物标志物如 LC3-II、Beclin-1 等可用于评估自噬活性，但需提高其对 CSC 亚群的特异性。此外，联合治疗策略如自噬抑制剂与免疫治疗、放疗 ...

E. Napoletano is a former registered financial advisor and award-winning author and journalist. Managing Editor, Global Data and Automation for Forbes Advisor. Mitch has more than a decade of ...

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