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Whether the use of balanced multielectrolyte solution (BMES) in preference to 0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney injury or death is ...
Effects of fluid resuscitation with 0.9% saline versus a balanced electrolyte solution on acute kidney injury in a rat model of sepsis. Crit Care Med 2014;42(4):e270-e278. Crossref.
Those who received balanced solution were 0.4% (95% confidence interval [CI], -2.1% to 2.9%) more likely to develop AKI than those who received saline. Clinically, patients in the balanced ...
BEST-Fluids received balanced crystalloid and saline solutions at no charge from Baxter Healthcare, which markets Plasma-Lyte 148. The study received no other commercial funding.
Compared with standard saline IV fluids, deceased donor kidney transplant recipients who instead received a balanced low-chloride crystalloid solution had a 25% lower relative risk for ...
On the other hand, the balanced solution is much closer to normal blood levels of sodium and chloride. During a two-year period, Vanderbilt researchers carried out two studies involving 28,000 ...
A total of 14.3% of the patients treated with a balanced crystalloid solution experienced a major adverse kidney event compared with 15.4% of patients given saline intravenous fluids (marginal ...
Balanced fluids, rather than saline, ... 14.3 percent of the patients treated with a balanced crystalloid solution experienced a major adverse kidney event compared with 15.4 percent of patients ...
The SALT-ED trial (Saline against Lactated Ringer’s or Plasma-Lyte in the Emergency Department) lasted 16 months and involved 13,347 patients; 6,708 (50.3%) were assigned to balanced ...
Among patients on balanced solutions, 16.8 percent died in hospital, versus 17.3 percent who received saline suggesting that one life is saved for every 250 patients treated.