We constructed two types of packaging constructs, using pCA as a backbone, for gag-pol, and env, containing only the coding region of each open reading frame . pCA is a mammalian expression vector ...

To efficiently remove contaminating helper virus from the vector, a helper virus whose packaging signal is flanked by loxP sites was developed.7 In cells expressing the P1 phage Cre protein ...

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New plasmids will help accelerate and standardize lentiviral vector development from clinical to commercial manufacturing. WILMINGTON, Mass.--(BUSINESS WIRE)--Charles River Laboratories International, ...