The DNA of mammalian cells can be damaged by various endogenous and exogenous insults, leading, if unrepaired, to genomic instability. Recently it has become apparent that bacterial pathogens can ...

For functional analysis of genomic DNA of higher eukaryotes, stable cloning of large genomic fragments is well established in bacterial artificial chromosomes (BACs) and in P1-based artificial ...

The Bacterial Genomic DNA Isolation Kit was used to isolate genomic DNA from 1 mL overnight culture (1 x 10 9 cells) of the Gram negative bacteria E. coli (Lanes 1 and 2), the lysozyme-resistant ...

Whereas CRISPR is best at making small, targeted modifications to a genome, bridge RNA gives genetic engineers a power they’ve never had before—to add, remove, invert, or rearrange large ...

An obscure group of phages offers insights into elements of microbial warfare—and blueprints for new antibiotics.

Bacteria become 'genomic tape recorders', recording chemical exposures in their DNA. ScienceDaily . Retrieved May 27, 2025 from www.sciencedaily.com / releases / 2014 / 11 / 141113142006.htm ...

Bacterial Defense: DdmD and DdmE proteins use guide DNA to identify and degrade plasmids in bacteria. Genome Editing Potential: The guide DNA used in this system may be more stable and cost-effective ...

Bacteria and their viruses have been locked in battle for eons, as viruses try to inject their DNA into the bacterial genome and bacteria devise cunning methods (e.g. CRISPR) to defend themselves.

The genome structure—how genes are organized within DNA sequences in an organism—is fundamental to the processes and functions of organisms. A team at the University of Tokyo has developed a ...

“A typical bacterial genome is three million base pairs long, but time fragments the ancient DNA we recover to an average length of only about 30 to 50 base pairs,” said Christina Warinner ...