When bacterial DNA is labeled with radioactive atoms, it takes its own picture. Autoradiographs reveal that the bacterial chromosome is a single very long DNA molecule and show how it is duplicated ...

Within each HAC, the researchers designed sequences to bind centromeric proteins, which ensured that daughter cells would inherit the chromosome when the original cell divided. Specifically, they ...

Bacterial artificial chromosome (BAC) systems offer numerous benefits. These roomy vectors can contain an entire gene and all of its associated regulatory elements, allowing scientists to easily ...

and allowed to compete for hybridization sites on either metaphase chromosomes (left) or an array of BAC (bacterial artificial chromosome) clones that represent thousands of small DNA segments ...

Bioinformaticians have established that the genes in bacterial genomes are arranged in a meaningful order. They describe that the genes are arranged by function: If they become increasingly important ...

Accordingly, their position influences how their activity changes with the growth rate. Are genes distributed randomly along the bacterial chromosome, as if scattered from a salt shaker? This opinion, ...

Purified soil DNA is used to construct small-insert libraries in plasmid vectors or large-insert libraries in cosmid, fosmid or BAC (bacterial artificial chromosome) vectors. Small-insert ...

In a paper published in Science, researchers show that transposons can target and insert themselves at the ends of linear ...

Artificial human DNA ... Scientists have already synthesized bacterial genomes and portions of human chromosomes, and future advancements could make it possible to generate entire human genomes ...