A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

Fu and colleagues used Vibrio cholerae bacteria as a model for studying the plasmid defense system known as DdmDE, consisting ...

Grow bacterial clones, having plasmid DNA of interest Inoculate single clones into a 96-well, 2 mL, square-well plate holding 1.2 mL/well Terrific broth (TB) with suitable antibiotic(s) Grow cells ...

Imported seafood may be spreading colistin-resistant “superbugs” into U.S. kitchens as a new study warns of rising antibiotic ...

An interdisciplinary study reveals a unified model for plasmid distribution in bacterial cell division. November 15, 2022. Cell Biology Microbiology (B&M) Using a combination of biology and ...

Some bacteria already contained a circular piece of DNA, called a plasmid, which carries antibiotic-resistance genes. Those resistant cells (green) pass the plasmid to sensitive cells (red).

Ott, L., et al. (2024) Dietary zinc supplementation inhibits bacterial plasmid conjugation in vitro by regulating plasmid replication (rep) and transfer (tra) genes. Genetics and Molecular Biology ...

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.