The structures of the isolated compounds were deduced mainly from 1 H and 13 C NMR spectroscopic data at 300 and 75.4 MHz, respectively, with the aid of 1 H, 1 H-COSY, 13 C, 1 H-COSY-1 J (CH) and 13 C ...

In chemistry and drug discovery, compound promiscuity is a controversial issue and often viewed differently. On the one hand, promiscuity has a clear-cut negative connotation, as promiscuous behavior ...

The estrogenicities of 10 compounds found as impurities in industrial grade bisphenol A (BPA) were measured by yeast two-hybrid assays incorporating the human estrogen receptor α (hERα) or the medaka ...

A further series of compounds derived from an arylpyrazole structure was reported in 2006. 82 These compounds bind the glucocorticoid receptor with specificity and relatively high affinity ...