More specifically, high levels of BMP signaling are required for a ventral fate while low levels are required for a dorsal one. FIGURE 1. Canonical BMP signaling pathway. BMP ligands (yellow and green ...

As a result, we found 10 fibrotic signaling pathways that are closely related to the activation, proliferation, invasion, migration, and promotion of apoptosis of HCC cells. In addition, we found that ...

two key components of the Hippo pathway, highlighting its role in orchestrating BMP responses via the collagen matrix. Our findings highlight the importance of DDR2 in modulating BMP signaling.

This research underscores the importance of the BMP (Bone Morphogenetic Protein) signaling pathway in dental development ... play a crucial role in bone and cartilage development.

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Our results uncover how FOXG1 integrates extrinsic signalling via the FGF pathway to regulate the sequential generation of neurons, astrocytes, and oligodendrocytes in the cerebral cortex. A ...

During development, stem and progenitor cells gradually commit to differentiation pathways. Cell fate decisions ... through paracrine or autocrine signalling mechanisms, induce cells that have ...

A monoclonal mouse against αSMA (M0851) was from DAKO, and a monoclonal rabbit anti-cleaved caspase-3 (Asp175; 5A1E) was from Cell Signalling Technology. All experimental animal protocols were ...

Elevated PKA competitively inhibits PDE9A degradation, with PDE9A accumulation further disrupting the balance between cGMP-cAMP signalling pathways. PDE9A inhibition via Bay 73-6691 or CHIP ...

Time-series RNAseq revealed 607 genes with 24-hour patterns of expression representing several essential pathways in IVD physiology. Mice with conditional knockout of Bmal1 in their disc cells ...

Innovations in cartilage regeneration, including autologous chondrocyte implantation and biomimetic scaffolds, address the limitations of self-repair, and bone regeneration is being enhanced through ...